Description
Versatile, Affordable, Easy-to-Use, and Almost Hands-Free
The 310 Genetic Analyzer – the ideal alternative to gel-based DNA analysis for any research, clinical, forensic lab, or schools for teaching purposes – enables you to automate applications from de novo sequencing to SNP validation and linkage mapping. This versatile analyzer is so easy to use, that once it is installed and you have completed our short training course, all you have to do is load your samples, set up the Data Collection software and click the Start button.
Integrated Data Analysis Tools Reduce Time-to-Results
The 310 Genetic Analyzer software suite allows you to generate more meaningful data with less work.
The software suite includes (for U.S. customers, this suite also includes tools that assist with FDA 21CFRpart 11 compliance requirements):
- Data Collection Software (supplied with the instrument) – Manages your instrument setup, controls instrument operations, allows real-time data visualization, and performs diagnostics. Features include auto-analysis with Sequencing Analysis Software, flexibility to use any choice in dye set option, and optimized sequencing run modules that enable you to perform many different applications.
- Sequencing Analysis Software – Performs basecalling; assigns quality values; trims, displays, edits, and prints DNA sequencing data using the KB™ basecaller software.
- Seqscape® Software – A software program specifically designed to support re-sequencing projects data analysis.
- GeneMapper® Software – Enables configurable, automated allele calling. The closely related GeneMapper®ID Software is specifically designed for human-identity applications.
- MicroSeq® Software – Enables you to compare the sequence of an unidentified bacteria or fungi to a validated library for positive identification and taxonomic classification.
Extensive, Experienced Support
Solutions offered to you by the 310 Genetic Analyzer extend beyond just technologies and chemistry. We also have the industry’s most experienced and knowledgeable team of support specialists to help you get the most out of your instruments, reagents, and research.
Applied-Biosystems Sequencing Instruments
Easy Instrument Set-up
Simply install the capillary, load the gel pump with polymer, place your samples in the autosampler tray, and
instrument set-up is complete.
Automated Gel Loading
The 310 system gel pump automatically fills the capillary with either DNA sequencing or fragment
analysis polymer. Switching from DNA sequencing to PCR product analysis is as easy as installing a
different capillary and polymer.
Automated Sample Loading
The autosampler, using an electrokinetic injection, sequentially loads each sample into the capillary for
electrophoresis.
ABI PRISM® Separation Polymers
The 310 Genetic Analyzer separates DNA fragments by using POP™ Performance Optimized Polymers, which
yield extremely reproducible results. The POP™ polymer family includes POP-6™ polymer for high-resolution
applications such as DNA sequencing, and POP-4™ polymer, which provides faster runs for applications such as
microsatellite analysis, AFLP® Kit, and rapid sequencing. We also offer a general purpose polymer that is
user-modifiable for a variety of genotyping applications. This polymer allows you
to alter polymer concentration or add reagents such as urea or glycerol.
Multiple Dye Detection
The 310 Genetic Analyzer simultaneously detects up to five different fluorescent dyes in a single capillary
providing multicolor analysis. This process is further simplified by fluorescent terminator sequencing chemistry,
which allows you to perform single tube sequencing reactions. For genotyping, multicolor detection
increases throughput by allowing you to multiplex several PCR samples labeled with multiple dyes. A labeled
internal standard can be added to each run to provide exceptional fragment sizing reproducibility.
ABI PRISM® System Integration
The 310 Genetic Analyzer is fully integrated with proven ABI PRISM® reagents and software for DNA
sequencing and genotyping applications. The ABI PRISM® 310 Analyzer Windows®-compatible system allows
data to be easily transferred between different platforms such as the ABI PRISM® 3100 and 3100-Avant Genetic
Analyzers as well as to downstream analysis software, the industry standards for automated genotyping, sequencing,
and mutation analysis.
